Design and Analysis of a High-Performance Capsule-Shaped 2D-Photonic Crystal Biosensor: Application in Biomedicine

Authors H. Tayoub1,2, A. Hocini1, A. Harhouz1
Affiliations

1Laboratoire d’Analyse des Signaux et Systèmes, Department of Electronics, University of M’Sila BP.166, Route Ichebilia, M’Sila, 28000, Algeria

2Research Center in Industrial Technologies CRTI, P.O.BOX:64, Cheraga 16014, Algiers-Algeria

Е-mail hadjira.tayoub@univ-msila.dz
Issue Volume 13, Year 2021, Number 6
Dates Received 12 September 2021; revised manuscript received 02 December 2021; published online 20 December 2021
Citation H. Tayoub, A. Hocini, et al., J. Nano- Electron. Phys. 13 No 6, 06005 (2021)
DOI https://doi.org/10.21272/jnep.13(6).06005
PACS Number(s) 07.07.Df, 42.79.Pw
Keywords PhC biosensor, Blood components, Cancer, Sensitivity (11) , Quality-factor, Capsule-microcavity.
Annotation

In this paper, a novel capsule-shaped two-dimensional photonic crystal (2D-PhC) biosensor, which can sense different body fluids and cancer cells for biomedical applications, has been successfully proposed, designed, and evaluated. Simulation and analysis using Plane Wave Expansion (PWE) method and Finite-Difference Time-Domain (FDTD) algorithm have been done to detect blood components and cancer cells, in which samples are taken in liquid form and penetrate a capsule-shaped cavity. It consists of a capsule-shaped cavity coupled to two waveguides, and the sensing region has a capsular geometry and is positioned in the central region of the optical waveguide. The sensing mechanism of the present biosensor is based on changing the refractive index of the analyte. A high sensitivity of 609.25 nm per refractive index unit (nm/RIU), a low detection limit of 3.9  10 – 6 RIU and a Q-factor of up to 107 are predicted for a specific sensor-array arrangement in the wavelength range of 1.4367 to 2.0233 m. These values demonstrate the potentiality of the proposed biosensor. To ensure the validity of the proposed biosensor, a comparison between the results of the present work and related literature for 2D-PhC biosensors has been made.

List of References