Design and Analysis of a High-Performance Capsule-Shaped 2D-Photonic Crystal Biosensor: Application in Biomedicine

Authors H. Tayoub1,2 , A. Hocini1 , A. Harhouz1

1Laboratoire d’Analyse des Signaux et Systèmes, Department of Electronics, University of M’Sila BP.166, Route Ichebilia, M’Sila, 28000, Algeria

2Research Center in Industrial Technologies CRTI, P.O.BOX:64, Cheraga 16014, Algiers-Algeria

Issue Volume 13, Year 2021, Number 6
Dates Received 12 September 2021; revised manuscript received 02 December 2021; published online 20 December 2021
Citation H. Tayoub, A. Hocini, et al., J. Nano- Electron. Phys. 13 No 6, 06005 (2021)
PACS Number(s) 07.07.Df, 42.79.Pw
Keywords PhC biosensor, Blood components, Cancer, Sensitivity (11) , Quality-factor, Capsule-microcavity.

In this paper, a novel capsule-shaped two-dimensional photonic crystal (2D-PhC) biosensor, which can sense different body fluids and cancer cells for biomedical applications, has been successfully proposed, designed, and evaluated. Simulation and analysis using Plane Wave Expansion (PWE) method and Finite-Difference Time-Domain (FDTD) algorithm have been done to detect blood components and cancer cells, in which samples are taken in liquid form and penetrate a capsule-shaped cavity. It consists of a capsule-shaped cavity coupled to two waveguides, and the sensing region has a capsular geometry and is positioned in the central region of the optical waveguide. The sensing mechanism of the present biosensor is based on changing the refractive index of the analyte. A high sensitivity of 609.25 nm per refractive index unit (nm/RIU), a low detection limit of 3.9  10 – 6 RIU and a Q-factor of up to 107 are predicted for a specific sensor-array arrangement in the wavelength range of 1.4367 to 2.0233 m. These values demonstrate the potentiality of the proposed biosensor. To ensure the validity of the proposed biosensor, a comparison between the results of the present work and related literature for 2D-PhC biosensors has been made.

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