Design and Fabrication of Polymer-Ceramic Nanocomposites Materials for Bone Tissue Engineering

Authors L.F. Sukhodub , K. Dyadyura  

Sumy State University, 2, Rymskyi-Korsakov Str., 40007 Sumy, Ukraine

Issue Volume 10, Year 2018, Number 6
Dates Received 22 July 2018; revised manuscript received 28 November 2018; published online 18 December 2018
Citation L.F. Sukhodub, K. Dyadyura, J. Nano- Electron. Phys. 10 No 6, 06003 (2018)
PACS Number(s) 87.85.J –, 87.64.Bx, 87.64.Ee
Keywords Nanohydroxyapatite, Scaffolds, Composites (15) , Biodegradable polymers, Regenerative medicine, Tissue engineering.

This study intends to present a review of the different types of ceramic-polymeric nanocomposites. The present article has as its main goal to analyze the most recent reported studies based on polymer-ceramic nanocomposites produced for bone replacement and regeneration. Scaffold fabrication methodology, mechanical performance, biocompatibility, bioactivity, and potential clinical translations are discussed. Some of the most popular processing methods to produce bioceramic structures are discussed, with an emphasis on the production of HA scaffolds. The numerous scaffold processing methods currently adopted to fabricate porous bioceramic structures and their current limitations, are discussed and comparisons are made to understand the rationale and motivation for the research. Structural, morphology, micrograph and chemical composition of this nanocrystalline composites were characterized by XRD, AFM, SEM and FTIR, respectively.

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