Enhancing X-ray Therapy: A Monte Carlo Study of Bismuth Sulfide Nanomaterials
| Authors | L. Kahia Aoul1, A.S.A. Dib2, S. Chiali1, A. Djelloul3 |
| Affiliations |
1Université Oran1 Ahmed Ben Bella, Oran, Algeria 2Université des Sciences et de la Technologie d’Oran Mohamed Boudiaf, USTO-MB, BP 1505 EL M’naouer, 31000 Oran, Algeria 3Centre de Recherche en Technologie des Semi-Conducteurs pour l’Energétique ‘CRTSE’, 02 Bd Frantz Fanon, BP 140, 7 Merveilles, Alger, Algérie |
| Е-mail | ahiaoual@outlook.com |
| Issue | Volume 17, Year 2025, Number 4 |
| Dates | Received 18 April 2025; revised manuscript received 22 August 2025; published online 29 August 2025 |
| Citation | L. Kahia Aoul, A.S.A. Dib, et al., J. Nano- Electron. Phys. 17 No 4, 04032 (2025) |
| DOI | https://doi.org/10.21272/jnep.17(4).04032 |
| PACS Number(s) | 07.85.Qe, 43.58.Ta, 71, 78.40.Ri |
| Keywords | Radiation dose, Monte Carlo code, Nanomaterials (NMs), Tumor. |
| Annotation |
This study performs a numerical simulation of brain radiation therapy with a deep tumour at its centre using the Monte Carlo simulation program Geant4. The primary goal is to analyze the effect of nanomaterials (NMs) injected into the tumour on the dose and amount of radiation absorbed by the tumour. We built a spherical tumour measuring 1.5 cm in diameter in the middle of an adult human head while considering their chemical compositions and proportions. We are interested in studying the effects of adding bionanomaterials such as Gold nanoparticles (AuNP), hafnium oxide (HfO2), cerium oxide (CeO2), tantalum oxide (Ta2O5) and bismuth sulfur (Bi2S3) to the amount absorbed during an external exposure at a wavelength of energy ranging from 10 keV to 200 keV. The findings demonstrate that an absorbable dose improvement of 5.5 is obtained with a low concentration of 2% Bi2S3 nanoparticles inside the tumour, nearly four times with CeO2 nanoparticles and slightly more than three times with AuNPs. According to our results, Bi2S3 and CeO2 provide more enhancement in Radiotherapy than the most well-known materials in the literature, such as AuNPs. |
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