Selective Electrochemical Sensor Using Screen-Printed Carbon Electrode (SPCE) for Dopamine Detection in Neutral Condition

Authors L.M. Permatasari , K.A. Madurani , F. Kurniawan

Laboratory of Instrumentation and Analytical Sciences, Chemistry Department, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember (ITS), 60111 Surabaya, Indonesia

Issue Volume 14, Year 2022, Number 3
Dates Received 15 March 2022; revised manuscript received 24 June 2022; published online 30 June 2022
Citation L.M. Permatasari, K.A. Madurani, F. Kurniawan, J. Nano- Electron. Phys. 14 No 3, 03021 (2022)
PACS Number(s) 82.47.Rs
Keywords Dopamine (DA), SPCE (2) , Voltammetry (3) , Neutral condition.

A selective electrochemical sensor for detecting dopamine (DA) has been studied using a screen-printed carbon electrode (SPCE). The performance of SPCE was characterized using cyclic voltammetry at pH 7.0 in 0.1M phosphate buffer solution. The measurement was done in a potential range of −7.5 to 1V at room temperature. The effect of DA concentration and scan rate was observed. The result showed that DA can be detected specifically by looking at its reduction peak signal at a potential of − 0.11 V,  = − 52.13 µA. The signal of DA was monitored without any interference signals from ascorbic acid, glucose, uric acid, paracetamol, and urea. The obtained calibration curve, which represents various concentrations of DA as a function of peak current, followed the linear equation with R2 = 0.992 and with R2=0.985. The limits of detection and sensitivity of SPCE for DA detection were 0.030 μM and 8.107 μAmm2μM – 1, respectively. The effect of scan rate demonstrated a diffusion-controlled behavior from the reaction between SPCE and DA. The repeatability study of SPCE showed an increase in the peak current value. This is due to DA poisoning, resulting in less precision of repeated measurements.

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