Authors | E.S. Adewi1, K. Sesime1, A.D. Hounsi1, P. Pissang2, S.A.S. Bonou3, K.J.B. Amewotepe1, M. Agbahoungbata3, M.M. Dzagli1,4, , V.A. Adedeji5, A.C. Ahyi6, M.A. Mohou1 |
Affiliations |
1Laboratoire LPMCS, Faculté Des Sciences, University of Lomé, 01BP1515 Lomé, Togo 2Laboratoire LaSBASE, ESTBA, University of Lomé, 01BP1515 Lomé, Togo 3Xrays Techniques Laboratory/Agence de Développement de Seme City X-TechLab, Seme, Bénin 4Centre d’Excellence Regional pour la Maîtrise de l’Electricité, University of Lomé, 01BP1515 Lomé, Togo 5Elizabeth City State University, USA 6Auburn University, National Coalition of Independent Scholars, USA |
Е-mail | mdzagli@gmail.com |
Issue | Volume 17, Year 2025, Number 3 |
Dates | Received 10 March 2025; revised manuscript received 20 June 2025; published online 27 June 2025 |
Citation | E.S. Adewi, K. Sesime, A.D. Hounsi, et al., J. Nano- Electron. Phys. 17 No 3, 03004 (2025) |
DOI | https://doi.org/10.21272/jnep.17(3).03004 |
PACS Number(s) | 81.07. – b, 87.85.Rs, 78.67. – n, 81.16. – c |
Keywords | ZnO nanoparticles, Green synthesis, Structural and optical characterization, Antimicrobial application. |
Annotation |
Tropical infectious diseases develop resistance to antibiotics. The integration of nanoparticles in drugs could fight against this scourge. ZnO nanoparticle (ZnONPs) possesses remarkable antimicrobial properties, and their synthesis using medicinal plants is cost-effective and eco-friendly. The use of leaves of newbouldias leavis, launaea taraxacifolia, and Combretum micranthum in medicine was demonstrated in Togo, and their extract can be used as reducing and stabilizing agents of nanoparticles. This study evaluates the potential antimicrobial activities of ZnONPs, biosynthesized using leaf extracts of the three medicinal plants. The structural and optical properties of ZnONPs were investigated using UV-Vis, fluorescence, XRD, SEM, and EDS. The antibacterial potential of ZnONPs was assessed using two clinical and reference strains of E. coli and S. aureus. Spectroscopic measurements revealed an absorption peak between 370 and 377 nm, while the excitation at 365 nm produced spectra ranging from 450–700 nm. XRD analysis revealed a hexagonal wurtzite structure with a size of 39.05 nm. SEM analysis reveals nanostructures agglomerated, whereas EDS confirms the presence of ZnO. Antimicrobial tests against S. aureus and E. coli showed clear inhibition zones. Plant-based synthesis improves the biomedical properties of ZnONPs and constitutes a route for their use in nanomedicine. |
List of References |