Nanocomposite Apatite-biopolymer Materials and Coatings for Biomedical Applications
| Authors | L.F. Sukhodub1 , G.O. Yanovska2 , L.B. Sukhodub1 , V.M. Kuznetsov2 , O.S. Stanislavov2 |
| Affiliations | 1 Sumy State University of Ministry Science and Education of Ukraine, 2, Rymsky-Korsakov St.,40007, Sumy, Ukraine 2 Institute of Applied Physics of National Academy of sciences of Ukraine, 58, Petropavlovska St., 40007, Sumy, Ukraine |
| Е-mail | l_sukhodub@yahoo.com, biophy@yandex.ua, vkuznetsov.ua@gmail.com |
| Issue | Volume 6, Year 2014, Number 1 |
| Dates | Received 16 December 2013; published online 06 April 2014 |
| Citation | L.F. Sukhodub, G.O. Yanovska, L.B. Sukhodub, et al., J. Nano- Electron. Phys. 6 No 1, 01001 (2014) |
| DOI | |
| PACS Number(s) | 87.85.J –, 87.64.Bx, 87.64.Ee |
| Keywords | Composite biomaterials, Hydroxyapatite, Coatings (10) , Chitosan, Alginate, XRD (92) , XRF, FTIR (30) , SEM (114) , TEM (76) . |
| Annotation | The microoverview paper describes synthesis and characterization of novel third generation composite biomaterials and coatings which correspond to the second structural level of human bone tissue (HBT) organization obtained at Sumy state university “Bionanocomposite” laboratory. To obtain such composites an animal collagen is usually used, which is not potentially safe for medical applications. That is why investigations were started using some other biopolymers to obtain composites close to the second level in the structural hierarchy of HBT. Proposed natural polymers (Na alginate, chitosan) are the most perspective because they have bacteriostatic properties for a vast number of aerobic and anaerobic bacteria, high biocompatibility towards the connective tissue, low toxicity, an ability to improve regenerative processes during wounds healing, degradation ability with the creation of chemotaxic activity towards fibroblasts and osteoblasts. The formation of nanosized (25-75 nm) calcium deficient hydroxyapatite (cdHA) particles in the polymer scaffold approaches the derived material to the biogenic bone tissue, which can provide its more effective implantation. The influence of the imposition of static magnetic field on brushite (CaHPO4·2H2O) crystallization was also investigated. It was shown that changing the magnetic field configuration could greatly affect crystallinity and texture of the derived particles. To increase the biocompatibility of existing medical implants (Ti–6Al 4V, Ti Ni, Mg) the technology for obtaining bioactive coatings with corresponding mechanical, structural and morphology characteristics is developed in our laboratory. In this direction coatings based on cdHA in combination with biopolymer matrices (Na alginate, chitosan,) are obtained in “soft” conditions using a thermal substrate technology. This technology was proposed by Japan scientists [1] and was sufficiently improved by us [2] in order to obtain coatings in the controlled mode. |
|
List of References |
Other articles from this number
1) Investigation of Water Cluster Structure Using Raman Spectra Temperature Dependences [01002-1-01002-4]2) Natural Dye Extracts of Areca Catechu Nut as dye Sensitizer for Titanium dioxide Based Dye Sensitized Solar Cells [01003-1-01003-4]
3) The Design of a Low Power MEMS Based Micro-hotplate Device Using a Novel Nickel Alloy for Gas Sensing Applications [01004-1-01004-5]
4) Synthesis, Characterization and Density Functional Study of LiMn1.5Ni 0.5O4 Electrode for Lithium ion Battery [01005-1-01005-5]
5) Simulation Study on the Open-Circuit Voltage of Amorphous Silicon p-i-n Solar Cells Using AMPS-1D [01006-1-01006-4]
6) Effect of Composition on Optical and Thermoelectric Properties of Microstructured p-type (Bi2Te3)x(Sb2Te3)1 – x Alloys [01007-1-01007-6]
7) Synthesis and Characterization of Nickel Ferrite: Role of Sintering Temperature on Structural Parameters [01008-1-01008-4]
8) Investigation of a Nanophotonic Sensor with Electrode Modified by Semiconductor Quantum Dots [01009-1-01009-7]
9) Getting of Nanocomposites Thin Films on the Basis of Carbazolefrom Gas Phase and their Properties [01010-1-01010-3]
10) A Planar Interdigital Sensor for Bio-impedance Measurement: Theoretical analysis, Optimization and Simulation [01011-1-01011-7]
11) Tribological Properties of Nano-dimensional Systems Containing Carbon Surfaces [01012-1-01012-12]
12) Nanoelectronics: Thermoelectric Phenomena in «Bottom-Up» Approach [01013-1-01013-9]
13) Effect of the Solvent on the Microstructure of Bi2Te3 Obtained Solvothermal Microwave-assisted Synthesis [01014-1-01014-6]
14) Analysis of the Thermal Conductivity of Polymer Nanocomposites Filled with Carbon Nanotubes and Carbon Black [01015-1-01015-6]
15) Synthesis of ZnSe Films by Hydrochemical Sedimentation Method [01016-1-01016-4]
16) Morphology and Electrochemical Properties of Thermal Modified Nanoporous Carbon as Electrode of Lithium Power Sources [01017-1-01017-6]
17) The Anomalous Increasing of the Anode Current in the Diode Structures [01018-1-01018-3]
18) Model Evaluation the Effect of Size, Shape and Surface Condition of Apatite Nanocrystals on the Deviation of Ca / P ratio from stoichiometric [01019-1-01019-5]
19) Constants of Electron-Phonon Interaction for Optical and Intervalley Phonons in n-Ge [01020-1-01020-5]
20) The Oscillator Strength of the Quantum Transitions in Multi-Resonant-Tunneling Structures Tours as Basic Elements of Quantum Cascade Lasers and Detectors in a Transverse Magnetic Field [01021-1-01021-6]
21) Experimental Modeling of the Electron Beam Focusing Regimesin the Axially-Symmetric Systems [010224-1-01022-8]
22) Anisotropic Chemical Reactor with Correlation Spectroscopic Control of Nanoparticles Size [01023-1-01023-4]
23) Automated System of Study Nonlinear Processes in Electro-vacuum Devices with Open Resonant Periodic Structures [01024-1-01024-5]
24) Surface-Kinetics-Controlled Ostwald Ripening of Plane Precipitates at Grain Boundaries [01025-1-01025-7]
25) MEV Energy Electrostatic Accelerator Ion Beam Emittance Measurement [01026-1-01026-3]
26) About one Approach to Blocking Goldstone Mode of Ferroelectric Liquid Crystal [01027-1-01027-5]
27) Landau Theory in the Region of First Order Phase Transitions [01028-1-01028-8]
28) Nucleation of Gold in the Electric Field on the Surface of Template [01029-1-01029-6]
29) Formation of Biphasic State in Vacuum-Arc Coatings Obtained by Evaporation of Ti-Al-Zr-Nb-Y Alloy in the Atmosphere of Nitrogen [01030-1-01030-3]
30) Magnetoresistive Properties of Quasi Granular Film Alloys FexPt1 –x at the Low Concentration of Pt Atoms [01031-1-01031-5]
31) The Electrical Conductivity of the Three-layer Polycrystalline Films Co / Ag(Cu) / Fe in the Conditions of Atoms Interdiffusion [01032-1-01032-5]
