Bioactive Polymer-apatite Coatings with Antimicrobial Properties on Model Titanium Implants

Автор(ы) L.F. Sukhodub1, L.B. Sukhodub1, M.O. Kumeda1, A.P. Denysenko1, M.I. Kravchenko2
Принадлежность

1Sumy State University, 2, Rymsky-Korsakov St., 40007 Sumy, Ukraine

2Sumy National Agrarian University, 160, Gerasim Kondratiev St., 40000 Sumy, Ukraine

Е-mail l.sukhodub@gmail.com
Выпуск Том 12, Год 2020, Номер 3
Даты Received 03 February 2020; revised manuscript received 15 June 2020; published online 25 June 2020
Ссылка L.F. Sukhodub, L.B. Sukhodub, M.O. Kumeda, et al., J. Nano- Electron. Phys. 12 No 3, 03025 (2020)
DOI https://doi.org/10.21272/jnep.12(3).03025
PACS Number(s) 87.85.J –, 87.64.Bx, 87.64.Ee
Ключевые слова Zinc sulfide, Alginate, Hydroxyapatite, Antibacterial properties, Thermal substrate deposition.
Аннотация

Bioactive hydroxyapatite (HA) coatings containing zinc sulfide (ZnS) and alginate (Alg) were obtained on model titanium substrates by thermal substrate deposition (TSD) method. HA-based coatings provide implants for bioactivity and ZnS acts as an antimicrobial agent. It is proved that the introduction of Alg into the ZnS structure reduces the particle size, which contributes to the increased antimicrobial activity of the coatings. The antimicrobial activity of ZnS and ZnS/Alg layers was investigated by agar diffusion microbiological method. ZnS and ZnS/Alg provide the growth inhibition zones for E. coli ATCC No. 25922-5 and 11 mm, for S. aureus ATCC No. 25923-5 and 10 mm, for K. pneumonia No. 93-7 and 12 mm, respectively. The morphology and structure of the coatings were determined by X-ray diffraction (XRD), X-ray fluorescence analysis (RFA) and scanning electron microscopy (SEM). The obtained data confirmed the formation of a single-phase ZnS layer on the HA surface. The results presented underline the formation of biocomposite coatings with the functions of biocompatibility and antimicrobial activity.

Список литературы